TB-500: The Flexibility & Tissue Repair Peptide
Promote tissue flexibility, reduce inflammation, and accelerate healing from chronic injuries.
Tissue Repair
Flexibility
Anti-Inflammatory
TB-500 (Thymosin Beta-4) is a naturally occurring peptide present in nearly all human and animal cells. It plays a crucial role in tissue repair, cell migration, and reducing inflammation. For men dealing with chronic injuries, stiffness, or slow-healing wounds, TB-500 offers a powerful solution.
Athletes particularly value TB-500 for its ability to maintain flexibility and promote recovery from overuse injuries that don’t respond to conventional treatments.
How TB-500 Works
TB-500 works by upregulating actin, a cell-building protein essential for tissue repair and regeneration. Key mechanisms include:
- Cell Migration: Helps repair cells travel to injury sites faster
- Actin Upregulation: Increases cellular building blocks for tissue repair
- Anti-Inflammatory: Reduces chronic inflammation that slows healing
- Angiogenesis: Promotes new blood vessel formation
- Tissue Flexibility: Improves elasticity of muscles and connective tissue
Unlike BPC-157 which works best locally, TB-500 has a systemic effect—it travels throughout the body and can heal multiple injury sites simultaneously.
TB-500 Benefits for Men
1. Improved Flexibility
Increases muscle and tissue flexibility, reducing stiffness and improving range of motion.
2. Chronic Injury Healing
Particularly effective for stubborn injuries that haven’t responded to other treatments.
3. Reduced Inflammation
Calms chronic inflammation that can cause ongoing pain and slow recovery.
4. Hair Regrowth
Some users report improved hair growth, particularly when combined with other treatments.
5. Cardiac Support
Research suggests benefits for heart tissue repair and cardiovascular health.
6. Wound Healing
Accelerates healing of skin wounds, surgical incisions, and burns.
Compare TB-500 to BPC-157
See how these two healing peptides compare in our complete peptide comparison chart.
TB-500 Dosing Protocol
| Phase | Dose | Frequency | Duration |
|---|---|---|---|
| Loading Phase | 4-8 mg/week | Split into 2 doses | 4-6 weeks |
| Maintenance | 2-4 mg/week | 1-2 doses | As needed |
Dosing Notes:
- TB-500 works systemically—injection location doesn’t need to be near injury
- Subcutaneous injection in stomach area is most common
- Loading phase builds concentration in tissues
- Maintenance phase sustains benefits
See our complete dosing guidelines.
TB-500 + BPC-157 Stack
The Ultimate Healing Stack
TB-500 and BPC-157 work through complementary mechanisms, creating powerful synergy:
- BPC-157: Local healing, angiogenesis, growth factors
- TB-500: Systemic healing, cell migration, flexibility
Together, they address injuries from multiple angles. This stack is particularly effective for:
- Chronic tendon issues (tennis elbow, Achilles tendinopathy)
- Post-surgical recovery
- Stubborn injuries that won’t heal
- Athletes needing full-body recovery
Learn more about stacking in our top peptides for men guide.
TB-500 Side Effects
TB-500 is generally well-tolerated. Potential side effects include:
- Temporary fatigue: Some users report tiredness during loading phase
- Head rush: Occasionally when standing quickly after injection
- Injection site irritation: Mild, temporary
TB-500 FAQ
Explore All Healing Peptides
Discover BPC-157, collagen peptides, and more in our Complete Guide to Peptides for Men.
This article is for informational purposes only. Consult a healthcare professional before starting any peptide regimen.